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Caspase-3 p17 subunit Antibody

Size

Caspase-3 p17 subunit Antibody

0.1ml

Catalog no.

bs-20363R

Price

263 EUR

Buy Caspase-3 p17 subunit Antibody at gentaur.com

Tested Applications

WB

Gene ID number

836

Modification(s)

None

Swiss Prot

P42574

French translation

anticorps

Immunogen range

30-55/277

Subcellular location

Cytoplasm

Concentration

1ug per 1ul

Conjugation

Unconjugated

Recommended dilutions

WB(1:100-1000)

Cross reactivity

Human, Mouse, Rat

Category

Primary Antibodies

Modification site(s)

Unmodified antibody

Clonality

Polyclonal antibody

Clone number

Polyclonal antibody

Target Antigen

Caspase-3 p17 subunit

Also known as

Caspase-3 p17 subunit PAb

Purification method

This antibody was purified via Protein A.

Long name

Caspase-3 p17 subunit Primary Polyclonal Antibody

Specificity

This is a highly specific antibody against Caspase-3 p17 subunit.

Cross reactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Source

This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human caspase-3 p17 subunit

Storage conditions

Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.

Properties

If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Synonym names

Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.

Background of the target antigen

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.