Immunoglobulin
IgG
NCBI GENE nr
836
Works with
Human
GENE symbol
CASP3
Ab raised in
Rabbit
Protein nr
P42574
Ncbi nr
P42574
Omim nr
77416852
French translation
anticorps
Type
Polyclonal
Vial with antibody
in solution
Source
Homo sapiens
Antibodie's label
unlabelled serum
Purity
Immunoaffinity Chromatography
Immuno application
Western Blot, immuno-histo-chemistry
Antigene name
caspase 3, apoptosis-related cysteine peptidase
Suspention, pH, azide
TBS, pH 7.4, 50% glycerol, 0.5 mg/mL BSA, 0.02% sodium azide.
Antibody advice
Caspase-3 antibody can be used in immunohistochemistry starting at 5 ug/mL.
Antigen
Caspase-3 antibody was made against amino acids 166 - 183 of Caspase-3 (Human).
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Keep at
Caspase-3 antibody should be stored long term (months) at -20 grades C and short term (weeks) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
Gene names
CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama
Gene info
Caspase 3 is synthesized as an inactive proenzyme that undergoes proteolytic cleavage to produce 2 subunits, termed p20 and p11. These subunits dimerize to form the active enzyme. Caspase 3 proteolytically cleaves and activates other proteins. Caspase 3 has been associated with apoptosis.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
