Alternative name5
N/A
Gene name
N/A
Gene name synonims
N/A
Concentration
N/A
Purification method
N/A
Species reactivity
Human
Host organism
Rabbit
Alternative name4
CASPASE-3
Category
Antibodies
Clonality
Polyclonal
Immunoglobulin isotype
Polyclonal IgG
Clone
Polyclonal antibody
Form/Appearance
Serum (Serum - liquid)
Alternative name2
RABBIT ANTI HUMAN CASPASE-3
Alternative name1
Anti-RABBIT ANTI HUMAN CASPASE-3
Alternative name3
Lapin ANTI Homo sapiens CASPASE-3
Tested for:
Immunohistology - Paraffin (IHC), Western Blot (WB)
Other gene names
CASP3; CASP3; CPP32; SCA-1; CPP32B; CPP32; CASP-3; CPP-32; SCA-1
Test
MBS Polyclonals supplies antibodies that are for research of human proteins.
Other names
caspase-3 preproprotein; Caspase-3; caspase-3; CASP-3; CPP-32; apopain; procaspase3; protein Yama; PARP cleavage protease; cysteine protease CPP32; SREBP cleavage activity 1; caspase 3, apoptosis-related cysteine protease; caspase 3, apoptosis-related cysteine peptidase; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Additional description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Storage and shipping
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. productone should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
CASPASE-3 This item recognises the Caspase-3 cell death protease (also known as CPP32, YAMA and apopain).Caspase-3 is a 32kD protein, activated during apoptosis by cleavage into 17kD and 11kD fragments. This item recognises both intact Caspase-3 and the 17kD fragment, but not the 11kD fragment. In immunohistochemical studies Caspase-3 expression has been shown to be widespread, but not present in all cell types. Differences in the level of Caspase-3 have been reported in cells of short-lived nature (e.g. germinal centre B cells) and those that are long lived (e.g. mantle zone B cells).
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
