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Caspase 3 Antibody, HRP Conjugated

Size

Caspase 3 Antibody, HRP Conjugated

0.1ml

Catalog no.

bs-0081R-HRP

Price

350 EUR

Buy Caspase 3 Antibody, HRP Conjugated at gentaur.com

Gene ID number

836

Conjugation

HRP

Excitation Emission

N/A

Modification site

None

Swiss Prot

P42574

Target Antigen

Caspase-3

Subcellular location

Cytoplasm

Tested applications

WB, IHC-P

French translation

anticorps

Modification

Unmodified

Immunogen_range

60-100/277

Clonality

Polyclonal

Concentration

1ug per 1ul

Additional conjugation

HRP Conjugated

Clone

Polyclonal antibody

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Crossreactivity

Human, Mouse, Rat, Bovine, Goat

Recommended dilutions

WB(1:100-1000), IHC-P(1:100-500)

Purification method

This antibody was purified via Protein A.

Long name

Caspase 3 Polyclonal Antibody, HRP Conjugated

Specificity

This is a highly specific antibody against Caspase-3.

Source

KLH conjugated synthetic peptide derived from human Caspase 3(Active)

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.

Antigen background

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.