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Caspase 3 Antibody, Cy5 Conjugated

Size

Caspase 3 Antibody, Cy5 Conjugated

0.1ml

Catalog no.

bs-0081R-Cy5

Price

350 EUR

Buy Caspase 3 Antibody, Cy5 Conjugated at gentaur.com

Gene ID number

836

Conjugation

Cy5

Modification site

None

Additional conjugation

Cy5.5

Swiss Prot

P42574

Target Antigen

Caspase-3

Subcellular location

Cytoplasm

French translation

anticorps

Modification

Unmodified

Clonality

Polyclonal

Immunogen_range

60-100/277

Concentration

1ug per 1ul

Excitation Emission

625,650nm/670nm

Clone

Polyclonal antibody

Tested applications

FCM, IF(IHC-P), IF(ICC)

Category

Conjugated Primary Antibodies

Host Organism

Rabbit (Oryctolagus cuniculus)

Crossreactivity

Human, Mouse, Rat, Bovine, Goat

Purification method

This antibody was purified via Protein A.

Long name

Caspase 3 Polyclonal Antibody, Cy5 Conjugated

Recommended dilutions

FCM(1:20-100), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Specificity

This is a highly specific antibody against Caspase-3.

Source

KLH conjugated synthetic peptide derived from human Caspase 3(Active)

Crossreactive species details

Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.

Synonyms

CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3

Storage conditions

Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Properties

If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.

Antigen background

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.