PubChem CID
N/A MDL Number
N/A CAS Number
N/A Formulation
N/A Storage Temp.
-20°C Molecular Weight
685.72 Shipping Conditions
Gel Pack Shelf Life
36 months Category
Biochemicals Purity
≥85% by HPLC Appearance
Lyophilzed solid Solubility/Reconstitution Instructions
DMSO (~ 200 mg/ml) Tagline
A caspase-3 inhibitor Molecular Formula
C₂₉H₄₀FN₅O₁₁S Handling
Protect from air and moisture Peptide sequence
Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK Alternate Name/Synonyms
Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. 
