Peptide sequence
N/A
Formulation
N/A
Molecular Weight
324.4
Storage Temp.
-20°C
PubChem CID
9840223
Shipping Conditions
Gel Pack
Shelf Life
36 months
CAS Number
220509-74-0
Category
Biochemicals
MDL Number
MFCD22581511
Appearance
Yellow solid
Purity
≥97% by HPLC
Solubility/Reconstitution Instructions
DMSO (~ 200 mg/ml)
Molecular Formula
C₁₄H₁₆N₂O₅S
Handling
Protect from air and light
Tagline
A specific caspase-3/7 inhibitor
Alternate Name/Synonyms
5-[(2S)-2-(methoxymethyl)pyrrolidin-1-yl]sulfonyl-1H-indole-2,3-dione
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.