MDL Number
N/A
Solubility/Reconstitution Instructions
N/A
CAS Number
N/A
Molecular Weight
668.7
Storage Temp.
-20°C
Appearance
Liquid
PubChem CID
16760394
Shipping Conditions
gel pack
Shelf Life
6-12 months
Purity
>98% by HPLC
Formulation
In DMSO (10 mM)
Category
Caspase Inhibitor
Tagline
Caspase-3 inhibitor
Molecular Formula
C₃₀H₄₁FN₄O₁₂
Handling
Protect from light and moisture
Peptide sequence
Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
Alternate Name/Synonyms
Z-DEVD-FMK, Caspase-3 inhibitor, Z-DEVD fluoromethylketone
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
