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CaspGLOWTM Fluorescein Active Caspase-3 Staining Kit

Size

CaspGLOWTM Fluorescein Active Caspase-3 Staining Kit

25 assays

Catalog no.

K183-25

Price

237 EUR

Buy CaspGLOWTM Fluorescein Active Caspase-3 Staining Kit at gentaur.com

Kit's other name

none

Storage condition

-20°C

Shipping condition

gel pack

Samples tested

Live cells

Maximum time can be stored

6-12 months

Species reactivity

see datasheet

Category

Apoptosis Assay Kit

Contents

• FITC-DEVD-FMK • Wash Buffer • Z-VAD-FMK

Applications

Sensitive detection of activated caspase:3 in living cells.

Kit's benefits

• Simple one-step procedure; takes only 1-2 hours • Fast and convenient • The FITC label allows for direct detection of the activated caspases in apoptotic cells

Description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

Highlights

• Detection method: Fluorescence microscopy, Flow cytometry and fluorescence plate reader (Ex. = 485 nm and Em. = 535 nm) • Species reactivity: Mammalian • Kit size: Convenient sizes (25 and 100 assays) • Applications: Sensitive detection of activated caspase:3 in living cells.

Kit's description

Activation of caspases plays a central role in apoptosis. The CaspGLOW™ Fluorescein Active Caspase-3 Staining Kit provides a convenient means for sensitive detection of activated caspase-3 in living cells. The assay utilizes the caspase-3 inhibitor, DEVD-FMK, conjugated to FITC (FITC-DEVD-FMK) as a marker. FITC-DEVD-FMK is cell permeable, nontoxic, and irreversibly binds to activated caspase-3 in apoptotic cells.