Caspase-3 inhibitor, Z-DQMD-FMK for cell activation

Size

Caspase-3 inhibitor, Z-DQMD-FMK for cell activation

1 mg

Catalog no.

2782-1

Price

142 EUR

Buy Caspase-3 inhibitor, Z-DQMD-FMK for cell activation at gentaur.com

Is it cell-permeable?

Y

Is this a salt?

No

Supplied with

N/A

CAS number

N/A

Tissue

cell

Storage condition

-20°C

Molecular weight

685.72

Shipping condition

Gel Pack

Maximum time for storage

36 months

Category

Biochemicals

Purification

≥85% by HPLC

Physical appearance

Lyophilzed solid

Reconstitute instructions

DMSO (~ 200 mg/ml)

Molecular formula

C₂₉H₄₀FN₅O₁₁S

Storage instructions

Protect from air and moisture

Peptide sequence

Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK

Other name

Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-​Asp(OMe)-fluoromethylketone

Description

Z-DQMD-FMK is a cell-permeable caspase-3 inhibitor. Inhibits MG-132-induced small cell lung cancer cell death in vitro.

Additional description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.