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Caspase-3 Substrate DEVD-pNA for cell activation

Size

Caspase-3 Substrate DEVD-pNA for cell activation

200 assays

Catalog no.

1008-200

Price

327 EUR

Buy Caspase-3 Substrate DEVD-pNA for cell activation at gentaur.com

Is this a salt?

No

Is it cell-permeable?

No

Reconstitute instructions

N/A

CAS number

N/A

Tissue

cell

Storage condition

-20°C

Molecular weight

638.58

Physical appearance

Liquid

Shipping condition

gel pack

Maximum time for storage

6-12 months

Purification

>98% by HPLC

Supplied with

In DMSO (4 mM)

Category

Caspase Substrate

Peptide sequence

Ac-Asp-Glu-Val-Asp-pNA

Molecular formula

C₂₆H₃₄N₆O₁₃

Storage instructions

Protect from light and moisture

Other name

Ac-DEVD-pNA, Caspase-3 Substrate, Colorimetric

Additional description

Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.For cells, cell lines and tissues in culture till half confluency.

Description

Ready-to-use colorimetric substrate for CPP32/caspase-3 and related caspases that recognize the amino acid sequence DEVD. The sequence DEVD is based on caspase-3 cleavage site in poly (ADP-ribose) polymerase (PARP). CPP32 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleavage from the peptide substrate DEVD-pNA, using a spectrophotometer or multi-well plate reader. The ready-to-use caspase substrate provides an economic alternative for researchers who perform large amounts of caspase assays.