Recombinant
Yes
Purity
N/A
Endotoxin Level
N/A
Concentration
N/A
Biological activity
N/A
Results
N/A
NCBI Gene ID #.
12367
NCBI Gene Symbol
CASP3
Gene Source
Mouse
Accession #
Q8BNT4
Shelf Life
1 year
Storage Temp.
-70°C
Source
E. coli
Shipping
gel pack
Synonyms
Caspase 3
Biomolecule/Target
Caspase-3
Group
recombinants
Latin name
Mus musculus
Activity (Specifications/test method)
300000 units/mg
Appearance
Lyophilized powder
Physical form description
Lyophilized powder
Additional source
Recombinants or rec. proteins
Handling
Centrifuge the vial prior to opening.
Molecular Weight
of large (17 kD) and small (11 kD) subunits
Usage
For Research Use Only! Not to be used in humans
Taglines
A cysteine-aspartic acid protease involved in apoptosis
Reconstitution Instructions
Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Alternates names
Caspase-3, Short name=CASP-3, Apopain, Cysteine protease CPP32, Short name=CPP-32, FLICE, Protein Yama, SREBP cleavage activity 1, Short name=SCA-1
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.