Available ordering format
AM1 4 , IgG
Molecular weight (expected | аpparent)
Refer to NCBI
to be determined
Store at -20°C.
Western Blot (WB)
Protein A/G purified.
anti-mouse secondary antibodies
Recombinant human Caspase-3 protein. UniProt: P42574
How to reconstitute
See included datasheet or contact our support service
To be added when available, antibody released in November 2016.
Recommended dilutions for use
Optimal concentrations should be determined by serial dilutions.
Provided in phosphate buffered saline, contains 0.08% sodium azide.
No confirmed exceptions from predicted reactivity known at the moment.
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Caspase-3 is involved in the activation cascade of caspases, this cascade is responsible for apoptosis execution. It cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase-3 belongs to the group of effector caspases that are involved in the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others._x000B_