PubChem CID
N/A
MDL Number
N/A
CAS Number
N/A
Formulation
N/A
Storage Temp.
-20°C
Molecular Weight
685.72
Shipping Conditions
Gel Pack
Shelf Life
36 months
Category
Biochemicals
Purity
≥85% by HPLC
Appearance
Lyophilzed solid
Solubility/Reconstitution Instructions
DMSO (~ 200 mg/ml)
Tagline
A caspase-3 inhibitor
Molecular Formula
C₂₉H₄₀FN₅O₁₁S
Handling
Protect from air and moisture
Peptide sequence
Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK
Alternate Name/Synonyms
Z-DQMD-FMK,Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.