NCBI Gene ID #.
NCBI Gene Symbol
Activity (Specifications/test method)
Physical form description
Recombinants or rec. proteins
Centrifuge the vial prior to opening.
of large (17 kD) and small (11 kD) subunits
For Research Use Only! Not to be used in humans
A cysteine-aspartic acid protease involved in apoptosis
Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Caspase-3, Short name=CASP-3, Apopain, Cysteine protease CPP32, Short name=CPP-32, FLICE, Protein Yama, SREBP cleavage activity 1, Short name=SCA-1
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.