Activity (Specifications/test method)
NCBI Gene ID #.
NCBI Gene Symbol
Physical form description
Recombinants or rec. proteins
Centrifuge the vial prior to opening.
large (17 kD) and small (11 kD) subunits
Reconstitute in PBS containing 15% glycerol.
For Research Use Only! Not to be used in humans
A cysteine-aspartic acid protease involved in apoptosis
Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, CPP-32, Protein Yama, SREBP cleavage activity 1, SCA-1
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.